Completed STS-1, 8, and 41C.
What i'm doing is running the missions in order. First, i run through the mission phase of the upcoming mission in easy, as if i'm running through it in a simulator training for the actual deal. Once i do that, then i'll run the whole mission from T-1:50:00 to touchdown in hard, as if i'm flying through an actual mission (i REALLY like floating around through the shuttle BTW, i've been waiting many years for any sim to have the ability to freely explore the 3D Cabin, so many thanks for that feature!!).
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